Laurent Pierot

Editor-in-Chief

Service de Radiologie, Hôpital Maison Blanche, 45, rue Cognacq-Jay, 51100 REIMS

 Tel: 03 26 78 75 66

Secr: 03 26 78 75 68

Fax: 03 26 78 35 31

Email:

Medical School: Faculty of Medicine Saint-Antoine (Paris)

Residency and Fellowship: Neurology and Radiology

Medical Doctor: 1990

Graduated in Radiology: 1990

1990-1993: Assistant, Department of Neuroradiology (Professor J. Chiras), La Salpetriere Hospital, Paris

1993-1995: Assistant, Department of Interventional Neuroradiology (Professor J. Moret), Foundation Rothschild Hospital, Paris

1995-2001: Head of the Department of Diagnostic and Therapeutic Neuroradiology, Foch Hospital, Suresnes, Paris

2001-present: Professor of Radiology, Faculty of Medicine, Reims

2001-present: Head of the Department of Radiology, University Hospital, Reims

2007-2011: President of the French Society of Neuroradiology (SFNR)

Clinical Activities

Interventional Neuroradiology:

Endovascular treatment of ruptured and unruptured intracranial aneurysms using coils, stents, remodelling technique, flow diverters, occlusion of the parent vessel
Endovascular treatment of brain AVMs using glue and Onyx
Endovascular treatment of dural fistulas using arterial and venous approaches
Endovascular treatment of acute stroke (intraarterial chemical and mechanical thrombolysis)
Endovascular treatment of intracranial and cervical arterial stenosis
Embolization of intracranial and cervical tumors (meningiomas, chemodectomas,…)
Interventional spine

Diagnostic Neuroradiology

Research

Principal Investigator in multiple prospective, multicenter trials:

Matrix 2004: multicenter, prospective, French trial dealing with the safety and efficacy of Matrix coils in the treatment of intracranial aneurysms
ATENA: multicenter, prospective, French trial dealing with the endovascular treatment of unruptured intracranial aneurysms (27 French centers, 649 patients)
BRAVO: multicenter, prospective, Swiss trial dealing with the use of Onyx in the endovascular treatment of brain AVMs
CLARITY: multicenter, prospective, French trial dealing with the endovascular treatment of ruptured aneurysms using GDC and Matrix coils (20 French centers, 833 patients)

Publications

Publications in International and French medical journals: 86 (French papers: 20; international papers: 66)

Oral presentations at international and French meetings: more than 200

Publication Fields:

Diagnostic and therapeutic neuroradiology
Imaging, classification and treatment of vascular malformations of the brain
Endovascular treatment of intracranial aneurysms, brain AVMs, dural fistulas
Imaging and endovascular treatment of spinal vascular malformations
MR imaging of cerebral and spinal diseases
Functional MR imaging

Editorial Activities

Journal of Neuroradiology: Associate Editor

Stroke: Section Editor (Interventional Radiology)

AJNR: Member of the Editorial Board

Neurosurgery: Reviewer

More Recent International Publications (in the past five years)

Follow-up of intracranial aneurysms selectively treated with coils: prospective evaluation of contrast-enhanced MR Angiography
L. Pierot, C. Delcourt , F. Bouquigny, D. Breidt, B. Feuillet, O. Lanoix, S. Gallas
AJNR Am J Neuroradiol, 2006, 27 (4): 744-749.
Preoperative embolization of a cervico-dorsal paraganglioma by direct percutaneous injection of ONYX® and endovascular delivery of particles
R.S. Quadros, S. Gallas, C. Delcourt, E. Dehoux, B. Scherperel, L. Pierot
AJNR Am J Neuroradiol., 2006, 27:1907-1909.
Endovascular Treatment of Intracranial Aneurysms with Matrix™ Detachable Coils : Immediate Post-treatment Results from a Prospective, Multi-Center Registry
L. Pierot, A Bonafé, S. Bracard, X. Leclerc, and investigators
AJNR Am J Neuroradiol, 2006, 27: 1693-1699.
fMRI study of problem-solving after severe traumatic brain injury
F. Cazalis, A. Feydy, R. Valabrègue, M. Pélégrini-Issac, L. Pierot, Ph. Azouvi.
Brain Injury, 2006, 20: 1019-1028.
Endovascular treatment of middle cerebral artery aneurysms as first option: a single center experience of 92 aneurysms
R. Quadros, S. Gallas, R. Noudel, P. Rousseaux, L. Pierot
AJNR Am J Neuroradiol, 2007, 28: 1567-1572.
Endovascular Treatment of Intracranial Aneurysms with Matrix™ Detachable Coils : Midterm Anatomical Follow-up from a Prospective, Multi-Center Registry
L. Pierot, X. Leclerc, A. Bonafé, S. Bracard, and Matrix Registry Investigators
AJNR Am J Neuroradiol, 2008, 29: 57-61.
Feasibility, Procedural Morbidity and Mortality, and Long-Term Follow-Up of Endovascular Treatment of 321 Unruptured Aneurysms.
S. Gallas, J. Drouineau, J. Gabrillargues, A. Pasco, C. Cognard, L. Pierot, D. Herbreteau
AJNR Am J Neuroradiol, 2008, 29: 63-68.
Clinical outcome of patients harbouring unruptured intracranial aneurysms treated by endovascular approach: results of the ATENA trial.
L. Pierot, L. Spelle, F. Vitry, for the ATENA investigators
Stroke, 2008, 39: 2497-2504.
First price of the Innovation Award (attributed by Stroke)
Endovascular treatment of intracranial aneurysms using Matrix Coils : Short and Mid-term results.
L. Pierot, X. Leclerc, A. Bonafé, S. Bracard, and Investigators
Neurosurgery, 2008, 63: 850-857.
Endovascular treatment of Unruptured Intracranial Aneurysms : Comparison of Safety of remodeling technique and standard treatment with coils.
L. Pierot, L. Spelle, X. Leclerc, C. Cognard, A. Bonafé, J. Moret
Radiology, 2009, 251: 846-855.
Incidence of basioccipital hypoplasia malformation type I: comparative morphometric study of the posterior cranial fossa.
R. Noudel, N. Jovenin, C. Eap, B. Scherpereel, L. Pierot, P. Rousseaux
J Neurosurg, 2009, 111: 1046-1052.
Immediate anatomical results after the endovascular treatment of unruptured intracranial aneurysms : analysis of the ATENA series.
L. Pierot, L. Spelle, F. Vitry, for the ATENA investigators
AJNR Am J Neuroradiol, 2010, 31: 140-144.
Immediate anatomical results after endovascular treatment of ruptured intracranial aneurysms: analysis of the CLARITY series.
L. Pierot, C. Cognard, F. Ricolfi, R. Anxionnat, for the CLARITY investigators
AJNR Am J Neuroradiol, 2010, 31: 907-911.
Similar safety in centers with low and high volumes of endovascular treatments of unruptured intracranial aneurysms: analysis in ATENA series.
L. Pierot, L. Spelle, F. Vitry, for the ATENA investigators
AJNR Am J Neuroradiol, 2010, 31: 1010-1014.
Vasospasm after aneurysmal subarachnoid hemorrhage: Recent advances in endovascular management.
L. Pierot, M. Aggour, J. Moret
Current Opinion in Critical Care, 2010, 16: 110-116.
Ruptured intracranial aneurysms: Factors affecting the rate and outcome of endovascular treatment complications in a series of 782 patients (CLARITY).
L. Pierot, C. Cognard, R. Anxionnat, F. Ricolfi, and CLARITY investigators
Radiology, 2010, 256: 916-923.
Abciximab treatment modalities for thromboembolic events related to aneurysm coiling.
M. Aggour, L. Pierot, K. Kadziolka, Ph. Gomis, J.-P. Graftieaux
Neurosurgery, 2010, 67 : 503-508.
Endovascular treatment of very small unruptured aneurysms: rate of procedural complications, clinical outcome, and anatomical results.
L. Pierot, C. Barbe, L. Spelle, and ATENA investigators
Stroke, 2010, 41: 2855-2859.
The remodelling technique for endovascular treatment of ruptured intracranial aneurysms had a higher rate of adequate occlusion than did conventional coil embolization with comparable safety.
L. Pierot, C. Cognard, R. Anxionnat, F. Ricolfi, and CLARITY investigators
Radiology, 2011, 258: 546-553.
Can flow divert stent devices prevent aneurismal rupture? Direct CCF following intracavernous carotid aneurysm treatment with Silk stent.
W. Mustafa, K. Kadziolka, R. Noudel, L. Pierot
Interventional Neuroradiology, 2010, 16: 4478-450.
Letter by Pierot regarding article “Flow-diverter stent for the endovascular treatment of intracranial aneurysms: a prospective study in 29 patients with 34 aneurysms”
L. Pierot
Stroke, 2011, 42: e38-39.
Safety and efficacy of balloon remodelling technique during endovascular treatment of intracranial aneurysms: Critical review of the literature
L. Pierot, C. Cognard, L. Spelle, J. Moret
AJNR Am J Neuroradiol (in press)
Results of embolization used as the first treatment choice in a consecutive non selected population of ruptured aneurysms. Clinical Results of the Clarity GDCTM study.
C. Cognard, L. Pierot, R. Anxionnat, F. Ricolfi, and CLARITY investigators
Neurosurgery (in press)
Mid-term anatomical results after endovascular treatment of ruptured intracranial aneurysms with GDC™ and Matrix™ coils: analysis of the CLARITY series.
L. Pierot, C. Cognard, F. Ricolfi, R. Anxionnat, on behalf of CLARITY group
AJNR Am J Neuroradiol (in press)